What are Melanocyte-Stimulating Hormones (MSH)?

Melanocyte-stimulating hormones (MSH) are part of a group of peptides involved in melanocortin signalling. They are relevant to pigmentation biology, but a basic hormone explanation should not be turned into a promise about a retail product or a guarantee of sun protection.

MSH and pigment cells

Melanocytes make melanin, a pigment that contributes to skin and hair colour. Melanocortin signalling is one influence on that process. The site’s existing mechanism article discusses synthetic peptide claims in more detail. Endogenous hormones, a studied analogue and a seller-labelled item are not automatically interchangeable.

Why the distinction matters for UV

Natural skin types vary in how readily they burn and tan. Melanin provides some protection, but ultraviolet radiation can still cause damage. Cancer Research UK advises sun protection regardless of a visible tan. A hormone pathway is not a substitute for shade, clothing and sunscreen.

Research versus merchandise

The EMA’s afamelanotide record concerns a specific authorised implant and medical condition; it does not verify online Melanotan 2 products. Read a scientific claim in its exact compound and study context.